Characterization of a Novel Reassortant Influenza A Virus (H2N2) from a Domestic Duck in Eastern China
Identifieur interne : 000044 ( 1968/Analysis ); précédent : 000043; suivant : 000045Characterization of a Novel Reassortant Influenza A Virus (H2N2) from a Domestic Duck in Eastern China
Auteurs : Mai-Juan Ma [République populaire de Chine] ; Xiao-Xian Yang [République populaire de Chine] ; Yan-Hua Qian [République populaire de Chine] ; Si-Yan Zhao [République populaire de Chine] ; Sha Hua [République populaire de Chine] ; Tie-Cheng Wang [République populaire de Chine] ; Shan-Hui Chen [République populaire de Chine] ; Guang-Yuan Ma [République populaire de Chine] ; Xiao-Yu Sang [République populaire de Chine] ; Lin-Na Liu [République populaire de Chine] ; Ai-Ping Wu [République populaire de Chine] ; Tai-Jiao Jiang [République populaire de Chine] ; Yu-Wei Gao [République populaire de Chine] ; Gregory C. Gray [États-Unis] ; Teng Zhao [République populaire de Chine] ; Xia Ling [République populaire de Chine] ; Jing-Lin Wang [République populaire de Chine] ; Bing Lu [République populaire de Chine] ; Jun Qian [République populaire de Chine] ; Wu-Chun Cao [République populaire de Chine]Source :
- Scientific Reports [ 2045-2322 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (immunologie), Anticorps antiviraux (sang), Canards (immunologie), Canards (sang), Canards (virologie), Chine, Grippe chez les oiseaux (immunologie), Grippe chez les oiseaux (sang), Grippe chez les oiseaux (virologie), Humains, Maladies de la volaille (immunologie), Maladies de la volaille (sang), Maladies de la volaille (virologie), Sous-type H2N2 du virus de la grippe A (génétique), Sous-type H2N2 du virus de la grippe A (immunologie), Sous-type H2N2 du virus de la grippe A (isolement et purification).
- MESH :
- génétique : Sous-type H2N2 du virus de la grippe A.
- immunologie : Anticorps antiviraux, Canards, Grippe chez les oiseaux, Maladies de la volaille, Sous-type H2N2 du virus de la grippe A.
- isolement et purification : Sous-type H2N2 du virus de la grippe A.
- sang : Anticorps antiviraux, Canards, Grippe chez les oiseaux, Maladies de la volaille.
- virologie : Canards, Grippe chez les oiseaux, Maladies de la volaille.
- Animaux, Chine, Humains.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Antibodies, Viral (immunology), China, Ducks (blood), Ducks (immunology), Ducks (virology), Humans, Influenza A Virus, H2N2 Subtype (genetics), Influenza A Virus, H2N2 Subtype (immunology), Influenza A Virus, H2N2 Subtype (isolation & purification), Influenza in Birds (blood), Influenza in Birds (immunology), Influenza in Birds (virology), Poultry Diseases (blood), Poultry Diseases (immunology), Poultry Diseases (virology).
- MESH :
- chemical , blood : Antibodies, Viral.
- chemical , immunology : Antibodies, Viral.
- geographic : China.
- blood : Ducks, Influenza in Birds, Poultry Diseases.
- genetics : Influenza A Virus, H2N2 Subtype.
- immunology : Ducks, Influenza A Virus, H2N2 Subtype, Influenza in Birds, Poultry Diseases.
- isolation & purification : Influenza A Virus, H2N2 Subtype.
- virology : Ducks, Influenza in Birds, Poultry Diseases.
- Animals, Humans.
Abstract
While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infection. We report the isolation of a novel influenza A virus (H2N2) cultured in 2013 from a healthy domestic duck at a live poultry market in Wuxi City, China. Sequence data revealed that the novel H2N2 virus was similar to Eurasian avian lineage avian influenza viruses, the virus had been circulating for ≥ two years among poultry, had an increase in α2,6 binding affinity, and was not highly pathogenic. Approximately 9% of 100 healthy chickens sampled from the same area had elevated antibodies against the H2 antigen. Fortunately, there was sparse serological evidence that the virus was infecting poultry workers or had adapted to infect other mammals. These findings suggest that a novel H2N2 virus has been circulating among domestic poultry in Wuxi City, China and has some has increased human receptor affinity. It seems wise to conduct better surveillance for novel influenza viruses at Chinese live bird markets.
Url:
DOI: 10.1038/srep07588
PubMed: 25533850
PubMed Central: 4274511
Affiliations:
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PMC:4274511Le document en format XML
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R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Beijing, 100071</wicri:regionArea><wicri:noRegion>100071</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Xiao Xian" sort="Yang, Xiao Xian" uniqKey="Yang X" first="Xiao-Xian" last="Yang">Xiao-Xian Yang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology</institution>, Beijing, 100071, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Beijing, 100071</wicri:regionArea><wicri:noRegion>100071</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>School of Public Health, Central South University</institution>, Changsha, Hunan, 410000 P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changsha, Hunan</wicri:regionArea><wicri:noRegion>Hunan</wicri:noRegion></affiliation></author><author><name sortKey="Qian, Yan Hua" sort="Qian, Yan Hua" uniqKey="Qian Y" first="Yan-Hua" last="Qian">Yan-Hua Qian</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Wuxi Center for Disease Control and Prevention</institution>, Wuxi, 214023, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Wuxi, 214023</wicri:regionArea><wicri:noRegion>214023</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Si Yan" sort="Zhao, Si Yan" uniqKey="Zhao S" first="Si-Yan" last="Zhao">Si-Yan Zhao</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Military Veterinary Research Institute, Academy of Military Medical Sciences</institution>, Changchun, 130122, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changchun, 130122</wicri:regionArea><wicri:noRegion>130122</wicri:noRegion></affiliation></author><author><name sortKey="Hua, Sha" sort="Hua, Sha" uniqKey="Hua S" first="Sha" last="Hua">Sha Hua</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics</institution>, Chinese Academy of Sciences, Beijing, 100101,<country>P. R. China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a6"><institution>University of Chinese Academy of Sciences</institution>, Beijing, 100049,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Tie Cheng" sort="Wang, Tie Cheng" uniqKey="Wang T" first="Tie-Cheng" last="Wang">Tie-Cheng Wang</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Military Veterinary Research Institute, Academy of Military Medical Sciences</institution>, Changchun, 130122, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changchun, 130122</wicri:regionArea><wicri:noRegion>130122</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Shan Hui" sort="Chen, Shan Hui" uniqKey="Chen S" first="Shan-Hui" last="Chen">Shan-Hui Chen</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Wuxi Center for Disease Control and Prevention</institution>, Wuxi, 214023, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Wuxi, 214023</wicri:regionArea><wicri:noRegion>214023</wicri:noRegion></affiliation></author><author><name sortKey="Ma, Guang Yuan" sort="Ma, Guang Yuan" uniqKey="Ma G" first="Guang-Yuan" last="Ma">Guang-Yuan Ma</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Wuxi Center for Disease Control and Prevention</institution>, Wuxi, 214023, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Wuxi, 214023</wicri:regionArea><wicri:noRegion>214023</wicri:noRegion></affiliation></author><author><name sortKey="Sang, Xiao Yu" sort="Sang, Xiao Yu" uniqKey="Sang X" first="Xiao-Yu" last="Sang">Xiao-Yu Sang</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Harbin, 150001,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Lin Na" sort="Liu, Lin Na" uniqKey="Liu L" first="Lin-Na" last="Liu">Lin-Na Liu</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Military Veterinary Research Institute, Academy of Military Medical Sciences</institution>, Changchun, 130122, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changchun, 130122</wicri:regionArea><wicri:noRegion>130122</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Ai Ping" sort="Wu, Ai Ping" uniqKey="Wu A" first="Ai-Ping" last="Wu">Ai-Ping Wu</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics</institution>, Chinese Academy of Sciences, Beijing, 100101,<country>P. R. China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jiang, Tai Jiao" sort="Jiang, Tai Jiao" uniqKey="Jiang T" first="Tai-Jiao" last="Jiang">Tai-Jiao Jiang</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics</institution>, Chinese Academy of Sciences, Beijing, 100101,<country>P. R. China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gao, Yu Wei" sort="Gao, Yu Wei" uniqKey="Gao Y" first="Yu-Wei" last="Gao">Yu-Wei Gao</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Military Veterinary Research Institute, Academy of Military Medical Sciences</institution>, Changchun, 130122, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changchun, 130122</wicri:regionArea><wicri:noRegion>130122</wicri:noRegion></affiliation></author><author><name sortKey="Gray, Gregory C" sort="Gray, Gregory C" uniqKey="Gray G" first="Gregory C." last="Gray">Gregory C. Gray</name><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Duke Infectious Disease & Duke Health Institute, Duke University Medical Center</institution>, Durham, NC, 27710,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Teng" sort="Zhao, Teng" uniqKey="Zhao T" first="Teng" last="Zhao">Teng Zhao</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology</institution>, Beijing, 100071, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Beijing, 100071</wicri:regionArea><wicri:noRegion>100071</wicri:noRegion></affiliation></author><author><name sortKey="Ling, Xia" sort="Ling, Xia" uniqKey="Ling X" first="Xia" last="Ling">Xia Ling</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Wuxi Center for Disease Control and Prevention</institution>, Wuxi, 214023, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Wuxi, 214023</wicri:regionArea><wicri:noRegion>214023</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Jing Lin" sort="Wang, Jing Lin" uniqKey="Wang J" first="Jing-Lin" last="Wang">Jing-Lin Wang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology</institution>, Beijing, 100071, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Beijing, 100071</wicri:regionArea><wicri:noRegion>100071</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Bing" sort="Lu, Bing" uniqKey="Lu B" first="Bing" last="Lu">Bing Lu</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Wuxi Center for Disease Control and Prevention</institution>, Wuxi, 214023, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Wuxi, 214023</wicri:regionArea><wicri:noRegion>214023</wicri:noRegion></affiliation></author><author><name sortKey="Qian, Jun" sort="Qian, Jun" uniqKey="Qian J" first="Jun" last="Qian">Jun Qian</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Military Veterinary Research Institute, Academy of Military Medical Sciences</institution>, Changchun, 130122, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changchun, 130122</wicri:regionArea><wicri:noRegion>130122</wicri:noRegion></affiliation></author><author><name sortKey="Cao, Wu Chun" sort="Cao, Wu Chun" uniqKey="Cao W" first="Wu-Chun" last="Cao">Wu-Chun Cao</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology</institution>, Beijing, 100071, P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Beijing, 100071</wicri:regionArea><wicri:noRegion>100071</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>School of Public Health, Central South University</institution>, Changsha, Hunan, 410000 P. R. China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>, Changsha, Hunan</wicri:regionArea><wicri:noRegion>Hunan</wicri:noRegion></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Viral (blood)</term><term>Antibodies, Viral (immunology)</term><term>China</term><term>Ducks (blood)</term><term>Ducks (immunology)</term><term>Ducks (virology)</term><term>Humans</term><term>Influenza A Virus, H2N2 Subtype (genetics)</term><term>Influenza A Virus, H2N2 Subtype (immunology)</term><term>Influenza A Virus, H2N2 Subtype (isolation & purification)</term><term>Influenza in Birds (blood)</term><term>Influenza in Birds (immunology)</term><term>Influenza in Birds (virology)</term><term>Poultry Diseases (blood)</term><term>Poultry Diseases (immunology)</term><term>Poultry Diseases (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antiviraux (immunologie)</term><term>Anticorps antiviraux (sang)</term><term>Canards (immunologie)</term><term>Canards (sang)</term><term>Canards (virologie)</term><term>Chine</term><term>Grippe chez les oiseaux (immunologie)</term><term>Grippe chez les oiseaux (sang)</term><term>Grippe chez les oiseaux (virologie)</term><term>Humains</term><term>Maladies de la volaille (immunologie)</term><term>Maladies de la volaille (sang)</term><term>Maladies de la volaille (virologie)</term><term>Sous-type H2N2 du virus de la grippe A (génétique)</term><term>Sous-type H2N2 du virus de la grippe A (immunologie)</term><term>Sous-type H2N2 du virus de la grippe A (isolement et purification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>China</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Ducks</term><term>Influenza in Birds</term><term>Poultry Diseases</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sous-type H2N2 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps antiviraux</term><term>Canards</term><term>Grippe chez les oiseaux</term><term>Maladies de la volaille</term><term>Sous-type H2N2 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Ducks</term><term>Influenza A Virus, H2N2 Subtype</term><term>Influenza in Birds</term><term>Poultry Diseases</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H2N2 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term><term>Canards</term><term>Grippe chez les oiseaux</term><term>Maladies de la volaille</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Canards</term><term>Grippe chez les oiseaux</term><term>Maladies de la volaille</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Ducks</term><term>Influenza in Birds</term><term>Poultry Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Chine</term><term>Humains</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infection. We report the isolation of a novel influenza A virus (H2N2) cultured in 2013 from a healthy domestic duck at a live poultry market in Wuxi City, China. Sequence data revealed that the novel H2N2 virus was similar to Eurasian avian lineage avian influenza viruses, the virus had been circulating for ≥ two years among poultry, had an increase in α2,6 binding affinity, and was not highly pathogenic. Approximately 9% of 100 healthy chickens sampled from the same area had elevated antibodies against the H2 antigen. Fortunately, there was sparse serological evidence that the virus was infecting poultry workers or had adapted to infect other mammals. These findings suggest that a novel H2N2 virus has been circulating among domestic poultry in Wuxi City, China and has some has increased human receptor affinity. 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Jiao</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Ma, Mai Juan" sort="Ma, Mai Juan" uniqKey="Ma M" first="Mai-Juan" last="Ma">Mai-Juan Ma</name></noRegion><name sortKey="Cao, Wu Chun" sort="Cao, Wu Chun" uniqKey="Cao W" first="Wu-Chun" last="Cao">Wu-Chun Cao</name><name sortKey="Cao, Wu Chun" sort="Cao, Wu Chun" uniqKey="Cao W" first="Wu-Chun" last="Cao">Wu-Chun Cao</name><name sortKey="Chen, Shan Hui" sort="Chen, Shan Hui" uniqKey="Chen S" first="Shan-Hui" last="Chen">Shan-Hui Chen</name><name sortKey="Gao, Yu Wei" sort="Gao, Yu Wei" uniqKey="Gao Y" first="Yu-Wei" last="Gao">Yu-Wei Gao</name><name sortKey="Hua, Sha" sort="Hua, Sha" uniqKey="Hua S" first="Sha" last="Hua">Sha Hua</name><name sortKey="Hua, Sha" sort="Hua, Sha" uniqKey="Hua S" first="Sha" last="Hua">Sha Hua</name><name sortKey="Jiang, Tai Jiao" sort="Jiang, Tai Jiao" uniqKey="Jiang T" first="Tai-Jiao" last="Jiang">Tai-Jiao Jiang</name><name sortKey="Ling, Xia" sort="Ling, Xia" uniqKey="Ling X" first="Xia" last="Ling">Xia Ling</name><name sortKey="Liu, Lin Na" sort="Liu, Lin Na" uniqKey="Liu L" first="Lin-Na" last="Liu">Lin-Na Liu</name><name sortKey="Lu, Bing" sort="Lu, Bing" uniqKey="Lu B" first="Bing" last="Lu">Bing Lu</name><name sortKey="Ma, Guang Yuan" sort="Ma, Guang Yuan" uniqKey="Ma G" first="Guang-Yuan" last="Ma">Guang-Yuan Ma</name><name sortKey="Qian, Jun" sort="Qian, Jun" uniqKey="Qian J" first="Jun" last="Qian">Jun Qian</name><name sortKey="Qian, Yan Hua" sort="Qian, Yan Hua" uniqKey="Qian Y" first="Yan-Hua" last="Qian">Yan-Hua Qian</name><name sortKey="Sang, Xiao Yu" sort="Sang, Xiao Yu" uniqKey="Sang X" first="Xiao-Yu" last="Sang">Xiao-Yu Sang</name><name sortKey="Wang, Jing Lin" sort="Wang, Jing Lin" uniqKey="Wang J" first="Jing-Lin" last="Wang">Jing-Lin Wang</name><name sortKey="Wang, Tie Cheng" sort="Wang, Tie Cheng" uniqKey="Wang T" first="Tie-Cheng" last="Wang">Tie-Cheng Wang</name><name sortKey="Wu, Ai Ping" sort="Wu, Ai Ping" uniqKey="Wu A" first="Ai-Ping" last="Wu">Ai-Ping Wu</name><name sortKey="Yang, Xiao Xian" sort="Yang, Xiao Xian" uniqKey="Yang X" first="Xiao-Xian" last="Yang">Xiao-Xian Yang</name><name sortKey="Yang, Xiao Xian" sort="Yang, Xiao Xian" uniqKey="Yang X" first="Xiao-Xian" last="Yang">Xiao-Xian Yang</name><name sortKey="Zhao, Si Yan" sort="Zhao, Si Yan" uniqKey="Zhao S" first="Si-Yan" last="Zhao">Si-Yan Zhao</name><name sortKey="Zhao, Teng" sort="Zhao, Teng" uniqKey="Zhao T" first="Teng" last="Zhao">Teng Zhao</name></country><country name="États-Unis"><noRegion><name sortKey="Gray, Gregory C" sort="Gray, Gregory C" uniqKey="Gray G" first="Gregory C." last="Gray">Gregory C. 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